Mk-677 / Ibutamoren. What is it?

All you need to know Mk-677/Ibutamoren

Although MK-677 is related to the class of SARM (selective androgen receptor modulators), it is not technically a SARM but a “secretagogue”.


It mimics the effects of human growth hormone (HGH).

HGH is one of the most important hormones for growth from childhood to adulthood. It also helps to stimulate muscle growth and fat metabolism. The benefits of HGH include muscle growth, improved skin, increased bone density, decreased cardiovascular risk, improved mood and sleep quality. As you get older, your natural production of HGH decreases, sometimes accelerated by certain factors such as poor nutrition, physical activity, sleep quality, stress, etc. 

MK-677 (also known as Ibutamoren or Nutrobal) is taken orally and strongly increases the production of human growth hormone in the body.

Mechanism of action

After ingestion, MK-677 sends signals to the pituitary gland to secrete more growth hormone. Unlike HGH injections where the hormone is directly injected, MK-677 stimulates the production of growth hormone in the organism and IGF-1 (insulin-like growth factor 1), which also stimulates protein synthesis and muscle growth.

Side effects of MK-677

MK-677 does not cause alteration in testosterone, estrogen or DHT levels. There are no androgenic side effects and it doesn't cause hair loss. Although uncommon, it can produce the following side effects: mild lethargy, fluid retention, increased appetite.


If accompanied by a proper diet and training routine, it achieves a rapid muscle growth and elimination of body fat. Users have reported gains of 2 to 10kg of muscle mass in 2 to 6 months. Other effects include increased strength, energy levels, sleep quality, sexual performance, bone density, heart health and anti-aging properties. For women, unlike other anabolics, it works the same way as in men without virilising side effects.

The increase in physical strength can be observed in 2 days but effects on body composition take a week on average.

MK-677 does not cause a decrease in the natural production of GH o desensitisation of the pituitary gland.

How to use MK-677  

To reap the full benefits of MK-677 you are looking at a cycle of anywhere between 6-12 months.

In conclusion, MK-677 is almost as effective as HGH injection with fewer potential negative side effects. It is much more economical than external HGH and does not need to be injected.


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