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Which PCT for Prohormone Cycle

Which PCT for a Prohormone Cycle 


In this article we will cover how you can run a successful cycle and recover properly, keep your gains and get your hormone levels back to normal, with the right PCT.  

Taking prohormones are one way to get the edge over your natural ability and they are a great option  for those not wanting to go the route of AAS (Androgenic anabolic steroids). The increase in strength, size and overall aplha mentality can be an addicting euphoria. However we must not underestimate  prohormone's effect on our body. Therefore to keep our health optimal, after a prohormone cycle it is important that proper Post Cycle Therapy is followed.

AAS users will often tout the likes of Nolvadex (tamoxifen citrate) or Clomid (clomiphene citrate).  There are known as SERMS (Selective androgen receptor modulators) and in most of Europe and  the United States they are prescription only; Nolvadex most commonly used for the treatment of breast cancer in women and Clomid used in fertility treatment. 

However because they are prescription drugs, they are illegal to buy without one. SERMs can also have side effects such as depression, reduced cognitive ability, blurred vision and mood swings. So, what can we do instead? We can use over the counter supplements, or in this case Online options.  First, let me explain the point of PCT and why we do it.

Why Run a PCT ? 

During a prohormone cycle, the level of androgens in the body drops, ( another way to say this is your HPTA is suppressed meaning your natural testosterone level declines. 

To compensate for this drop,  your body starts overproducing estrogen to try to balance the hormone levels.  Once the external hormone source is removed (you come to an end of your  prohormone cycle), your natural testosterone levels are still inhibited while your estrogen levels are  still above baseline. So you have finished your cycle and are now left with a decreased amount of testosterone and an increased amount of Estrogen, not ideal for muscle building is it ? 

When do you start PCT and for how long for?

With prohormone use PCT is usually started the day after your last dosage and should be run for at least 4 weeks. Once PCT has finished ideally you want to stay off prohormones for the same amount of days as your cycle length + pct length.

The factors relating to PCT are as follows;

HPTA Function
HPTA stands for Hypothalamus-Pituitary-Testicular-Axis.
The Hypothalamus is the centre of testosterone function, controlling the release of other hormones such as Gonadotropin releasing hormone (GnRH) and Luteinising hormone releasing hormone (LHRH).  These in turn signal the pituitary gland to release Luteinising Hormone (LH) which promotes the release of testosterone from the testes. It is Hypothalamus' ability to bind to the Androgen Receptors in muscle cells can lead to muscle growth. 

HPTA is important in keeping your hormone levels optimised, an effect known as Homeostasis. When one hormone is low, the hypothalamus recognises this and then, by way of homeostasis, tries to  balance out the levels. For example when estrogen levels are low, it stimulates the release of testosterone that will then convert to estrogen via aromatisation. This is known as the negative feedback loop. Once the balance is restored, the hypothalamus stops signaling the release of hormones.

When we come off a cycle, it is important that we not only try to assist the balance of these hormones, but try to control them as well.


This is most commonly known as "b*tch tits* or "man boobs" and unlike obese men where this is called by fat storage, in this case it is caused by the feminisation of the male body. This happens when the estrogen receptors in the areola and nipple become oversensitive due to the increase in overall estrogen. This can lead to breast tissue formation behind the nipple which can be felt as a small lump as wel as swelling of the areola giving it a smoother softer look.
Estrogen levels can also cause other problems, such as libido loss, mass loss and the closing of growth plates. This is why it is important that you DO NOT use prohormones before the age of 18, as it can hinder your development. 

Prolactin levels can be raised by the action of the steroid in the
pituitary as it suppresses dopamine production letting prolactin production
continue unchecked. This action can manifest as swollen, hard nipples that
sometimes will leak a clear fluid.

The Liver and Kidneys
Certain prohormones are methylated. The reason they are is because the methyl allows them to pass through the organs without breaking down. This makes them a good option on price as a lower dosage is needed They are also much more potent. The negative aspect of this is that in return it damages the liver and kidneys.

Blood Pressure
All hormones such as testosterone and estrogen have an effect on blood pressure. It regard to prohormones, it is usually the wet compounds that aromatise that increase blood pressure the most. This is due to the contribution of water retention. As more fluid is retained around the body, pressure on the circulatory system is increased causing a vasoconstriction affect. This in turn elevates your blood pressure as more force is needed to pump the blood around your body.

Blood pressure is also linked to kidney problems and as explained above, methylated compounds can have a negative effect in this situation.
Therefore compounds that are both wet and methylated would be ideal to stay away from if you are worried about this side effect.

Prohormones can negatively affect your lipid profiles, increasing bad cholesterol (LDL) and lowering good cholesterol (HDL). Testosterone is derived from cholesterol after being converted to progesterone. Another critical role of testosterone in this equation is that it enabled HDL to remove excess LDL from the arterial wall and transport it to the liver for disposal. As natural testosterone production has stopped due to external hormone input. the effect on your lipid profiles is obvious.

Increasing androgens in the body enlarges the prostate via Benign
Prostatic Hyperplasia (BPH). This can negativelly affect your ability to urinate as well as the ability to get an erection. The nerves sitting on either side of the prostate send messages to the penis to initiate erections. The relaxation of the prostate also increases blood flow which affects erection health. A swelling of the prostate delays this blood flow and the messages reaching the penis.

Now that we know what can happen when using prohormones, let us build the foundation of an OTC (over the counter) PCT program.

We have several options when it comes to PCT, we will outline our top #2 choices below.  


Pure Labs CLOMADEX.  

This is such a versatile PCT as it can be used for pretty much any cycle, SARM/Prohormone/17a prohormone etc etc 


Pure Labs CLOMADEX is our #1 if you have ran a Prohormone or SARM cycle at the recommend dose and cycle length 


German Pharmaceuticals Ultimate PCT

This is our #2 choice for PCT protocol, but it is actually a more complete formula, great for if you have ran a heavy cycle or a longer cycle than you had planned ! Ultimate PCT contains 8 ingredients proven to increase Testosterone levels as well as decreasing estrogen levels ! 




German Pharmaceuticals Ultimate PCT, Your Perfect PCT protocol for advanced cycles 


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