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Methylclostebol

methylclostebol.png

Chemical Name(s):
4-chloro-17a-methyl-androst-4-ene-3b,17b-diol
1-androsten-3b-ol-17-one
4-Dehydroepiandrosterone


Synonyms: Promagnon 25, P-Mag, Methyl-clostediol
Chemical Formula: C20H29ClO2
Molecular Weight: NA
CAS: 5785-58-0
Q Qatio: NA
Anabolic #: NA
Androgenic #: NA
Oral Bioavailability: NA
AR Binding Affinity: NA
SHBG Binding Affinity: NA
Half Life: NA
Legal Status (US): Not listed as a controlled substance


Average Dose:
50-100mg/day

Average Cycle Length: 4-6 weeks

Another methylated prohormone, this one is often compared to (and mistaken for) a halodrol clone, though there is an important structural difference. P-mag lacks the C1-2 double bond common to boldenone derivatives like h-drol, boldione, dbol and M1,4ADD, having only a C4-5 (delta-4) double bond which makes it a closer structural relative of testosterone and methyl testosterone. The difference becomes apparent when we look at what each one becomes in vivo: where some h-drol is metabolised via 3b-HSD to oral turinabol, p-mag becomes methylated clostebol. A 4-chloro group is common to both drugs, which will make both poor substrates for the aromatase cytochrome P-450 enzyme.

The target hormone of methyl-clostebol (shown above) appears to be moderately anabolic (about half as strong as methyl test) and not very androgenic, with an overall A:A ratio of somewhere around 3:1 (compared to methyl test). This is a much less impressive ratio than OT, but A:A assays on rats are not definitive (and often conflicting), and compounds with a moderate amount of androgenicity tend to have more positive effects on mood energy and libido than those without.

What's most interesting for me is the choice in bringing out this particular diol prohormone, despite an apparent lack of legislation to prohibit the sale and possession of the target steroid above. I've checked the US Controlled Substances Act and the UK Misuse of Drugs Act, and it's not listed on either. This means that theoretically a willing manufacturer would be able to sell methyl clostebol just as legally as p-mag (which is not to say that that is particularly legal in the first place).

Despite being structurally and pharmacologically distinct from h-drol, I suspect p-mag will never quite escape comparisons with it's diene brother. While the effects of h-drol are most apparent in the last few weeks of a six week cycle, p-mag users tend to report more immediate size gains, with a lack of additional weight added in the last couple of weeks. Libido tends to remain more positive, likely due to the more androgenic qualities of the drug.

The aforementioned positive attributes and the possibility of short cycle durations would make this an excellent choice for a first cycle, though as with any methyl it is a good idea to educate yourself about the possibilities of hepatic impairment (watch out for yellowing of the eyes and skin, persistent itchiness especially of the palms and soles of the feet, and discontinue use and see a doctor if either of those occur).

While h-drol has proved popular for bulking, cutting, and recomping, p-mag is generally regarded as best when used for bulking.

 

Products With This Compound:

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