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Exemestane (Aromasin)

Chemical Name(s):
6-methyleneandrosta-1,4-dien-3,17- dione


Chemical Formula: C20H24O2
Molecular Weight: 296
CAS: NA
Q Qatio: NA
Anabolic #: NA
Androgenic #: NA
Oral Bioavailability: Estimated at 15%
AR Binding Affinity: NA
SHBG Binding Affinity: NA
Half Life: 27 hours
Legal Status (US): Prescription only


Average Dose:
10-25mg/day


Average Cycle Length: 4-8 weeks

Characteristics
Exemestane is a steroidal aromatase inhibitor, known as a suicidal inhibitor because it permanently binds to the aromatase enzyme.


Exemestane is one of the most potent and expensive steroidal aromatase inhibitors currently available on the market. It is available by prescription only. The estrogen inhibition rate for exemestane varies from 85% of estradiol to 95% for estrone.


Exemestane is looked highly upon due to the fact it can be just as effective as Letrozole or Arimidex without causing such a rapid rebound of estrogen, which is a typical problem of non-suicidal aromatase inhibitors.


Exemstane is rarely dosed beyond 25mg/day as this appears to be a high enough dose to suppress estrogen by a significant amount. It can reach maximum estrogen suppression in as little as 7 days. Since it increases testosterone levels, some users may experience androgenic effects.


References
Anabolic Pharmacology
Seth Roberts (2009)



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