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1,4-AD (Boldione)


Chemical Name(s):
1,4-androstadiene-3b,17b-dione
androst-1,4-diene-3b,17b-dione
1,4-Androstenedione


Chemical Formula: C19H24O2
Molecular Weight: 284.4
CAS: NA
Q Qatio: NA
Anabolic #: NA
Androgenic #: NA
Oral Bioavailability: Estimated at 8%
AR Binding Affinity: NA
SHBG Binding Affinity: Low
Half Life: NA
Legal Status (US): Listed as a controlled substance


Average Dose:
800-1500mg/day standalone
400-1000mg/day when stacking
Average Cycle Length: 6 weeks

Characteristics
Boldione is NOT a 17-alpha alkylated steroid, therefore high doses must be taken to accommodate for its rapid excretion from the liver.


Boldione itself likely does not have any significant anabolic or androgenic value. However after interaction with the 17b-HSD enzyme, boldione is converted to the illegal anabolic steroid boldenone. Boldione can also be converted to 1-androstenedione (1-AD) and/or 1-testosterone after interaction with the 5a-reductase enzyme. These metabolites are where this pro-hormone gets most of its effects.


Since boldione is a dione, conversions to the more powerful steroid metabolites are expected to be near 15-20%, which is another reason why such high doses are needed to see results.


This pro-hormone (and its metabolites) do not convert very readily to estrogen, so an aromatase inhibitor would likely not be needed during a cycle.


Results can be expected to kick in slowly after several weeks. Moderate gains in size and strength should be expected. This compound also has a tendency to increase appetite, which makes it a good choice for bulking.
Side effects are minimal with boldione, but can become more noticeable with doses above 1000mg/day. Side-effects may include increases blood pressure and oily skin. Overall, results and side-effects would be similar to that of boldenone, including lean mass gains with low bloating. Because this steroid is non-17aa there should be less concern about it negatively affecting the HDL/LDL ratio.


Although this compound can be used as a standalone, it is recommended to stack this compound with an already active steroid, as the high doses of boldione will likely saturate most of the steroid conversion enzymes.


Common Clones:
BOLD by IForce
EQ-Plex by Competitive Edge Labs (CEL)
BOLD 200 by IForce
EQ-Jet by Molecular Development
P-Bold by Proven Products


References
“Criteria to distinguish between natural situations and illegal use of boldenone, boldenone esters and boldione in cattle: 1. Metabolite profiles of boldenone, boldenone esters and boldione in cattle urine.”
Bruno Le Bizec, Frédérique Courant, Isabelle Gaudin, Emanuelle Bichon, Blandine Destrez,
Robert Schilt, Rosa Draisci, Fabrice Monteau and François André
Steroids; Volume 71, Issues 13-14, December 2006, Pages 1078-1087
“An in vitro study on metabolism of 17β-boldenone and boldione using cattle liver and kidney subcellular fractions”
R. Merlanti, G. Gallina, F. Capolongo, L. Contiero, G. Biancotto, M. Dacasto and C. Montesissa
“Pathology of the testicle and sex accessory glands following the administration of boldenone and boldione as growth promoters in veal calves”
Cannizzo, F.T.(Universita degli Studi di Torino (Italy)); Zancanaro, G.; Spada, F.; Mulasso, C.; Biolatti
Nov 2007 Veterinary science and hygiene

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